Mounjaro (Tirzepatide) Injections

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Mounjaro (tirzepatide) is a medication that is administered through injections. It is used to help lower A1C levels in adults with type 2 diabetes, in conjunction with a proper diet and exercise regimen. The medication was approved by the U.S. Food and Drug Administration (FDA) on May 13, 2022. Mounjaro is the first and only dual-targeted treatment for type 2 diabetes, as it targets both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.

Mounjaro is a once-weekly injection that works to improve blood sugar control in adults with type 2 diabetes. It is intended to be used as an adjunct to diet and exercise, and it helps to lower A1C levels. A1C is a blood test that measures average blood sugar levels over the past two to three months. Lowering A1C levels is important for managing diabetes and reducing the risk of complications.

The recommended starting dose of Mounjaro is 2.5 mg injected subcutaneously, which means the injection is given just under the skin. It is available as a prefilled, single-dose pen, making it convenient for self-administration.

It is important to note that Mounjaro carries a warning of the risk of thyroid C-cell tumors. Therefore, it is crucial to discuss the potential risks and benefits of Mounjaro with a healthcare professional before starting treatment.

The availability of Mounjaro may vary, and it is always recommended to consult with a healthcare professional for the most up-to-date information on its availability and potential alternatives.

Please consult the prescribing information and consult with a healthcare professional for more detailed and personalized information about Mounjaro (tirzepatide) injections.

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What is Mounjaro?

Mounjaro is a once-weekly injection that is FDA approved to be used to decrease blood sugar (blood glucose) in adults who have type 2 diabetes. It should be used together with diet and exercise. Mounjaro has also been shown in clinical trials to be useful for weight loss.

Diabetes is a long term condition when your blood sugars (HbA1c) become too high because the body does not produce or use insulin normally.  Overtime high blood sugars can cause serious health problems including heart disease, vision loss and kidney disease.

Mounjaro works to reduce blood sugar levels by increasing your insulin production and also lowering the amount of sugar your liver makes. It also slows the rate food passes through your body which makes you feel full longer.

Mounjaro (Tirzepatide) is the first dual GIP/GLP-1 receptor agonist which means it works on the glucose-dependent insulinotropic polypeptide (GIP) receptors and the glucagon-like peptide-1 (GLP-1) receptors.

Mounjaro can be used as a single therapy or with other diabetes medicines including metformin, sulfonylureas or SGLT2 inhibitors.

It is not known if this medicine can be used in people who have had pancreatitis.

Mounjaro is not for use in people with type 1 diabetes.

Is Mounjaro used for weight loss?

• Mounjaro has also shown to help lose weight in overweight patients. It is currently in Phase 3 clinical trials for weight loss in adults who are overweight, obese or have weight related health issues. Mounjaro has received FDA  Fast Track designation to speed up its path for FDA submission for treating  adults with obesity, or overweight with weight-related health conditions.
• In the SURMOUNT-1 clinical trial the average weight loss after 72 weeks was 15% for the 5mg dose, 19.5% for the 10mg dose and 20.9% for the 15mg dose.What should I do if I miss a dose?
  

  What should I do if I miss a dose?

  Take the missed dose as soon as you remember it within 4 days after the missed dose. However, if more than 4 days have passed, skip the missed dose and continue your regular dosing schedule. Do not inject two doses within 3 days of each other.

• What are the side effects of Mounjaro?

  • nausea
  • diarrhea
  • decreased appetite
  • vomiting
  • constipation
  • upset stomach