Dronabinol (Marinol) Capsules USP

Dronabinol (Marinol) Capsules USP

Dronabinol (Marinol) Capsules USP is a medication that contains the active ingredient dronabinol, which is a synthetic form of delta-9 tetrahydrocannabinol (THC), the primary psychoactive component found in cannabis. It is used for various medical purposes, including the treatment of nausea and vomiting caused by chemotherapy in patients who have not responded to other antiemetic medications. It is also prescribed to stimulate appetite in patients with AIDS-related anorexia.

Dosage and Administration: Dronabinol capsules come in different strengths, including 2.5 mg, 5 mg, and 10 mg. The dosage depends on the individual patient’s condition and response to treatment. It is usually taken orally, with or without food, as directed by a healthcare professional. The capsules should be swallowed whole and not chewed or crushed.

Side Effects: Like any medication, Dronabinol capsules can cause side effects. Common side effects may include drowsiness, dizziness, mood changes, dry mouth, and gastrointestinal disturbances. It is important to report any severe or persistent side effects to a healthcare provider.

Warnings and Precautions: Dronabinol capsules should be used with caution in patients with a history of substance abuse, as it can be habit-forming. It should also be used cautiously in patients with a history of psychiatric disorders, as it can cause mood changes and exacerbate symptoms. Patients should avoid driving or operating machinery until they know how the medication affects them. It is important to inform the healthcare provider about any other medications, supplements, or herbal products being taken, as they may interact with Dronabinol capsules.

Recall Information: It is worth noting that there have been recalls of Dronabinol capsules in the past. For example, The Harvard Drug Group, LLC issued a voluntary nationwide recall of a single lot of Dronabinol Capsules, USP in June 2023. It is always important to stay updated with any recall information and follow the instructions provided by the manufacturer or healthcare provider.

Please consult a healthcare professional or refer to the medication’s package insert for more detailed and up-to-date information on Dronabinol (Marinol) Capsules USP.

Referrences

• medlineplus
• fda

What is dronabinol?

Dronabinol is a man-made form of tetrahydrocannabinol (THC), a psychoactive substance found in cannabis (also known as marijuana).

Dronabinol is used to treat loss of appetite that causes weight loss in people with AIDS.

Dronabinol is also used to treat severe nausea and vomiting caused by cancer chemotherapy. Dronabinol is usually given after medicines to control nausea and vomiting have been tried without success.

Syndros (Generic Dronabinol) Oral Solution

Warnings

Dronabinol may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have ever had depression or mental illness.

You should not use dronabinol capsules if you are allergic to sesame oil. You should not use dronabinol oral solution if you have had an allergic reaction to alcohol or if you also use disulfiram (Antabuse) or metronidazole (Flagyl).

Dronabinol can raise or lower blood pressure, especially in older adults or in people with heart problems.

How should I take dronabinol?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Tell your doctor if you feel an increased urge to use more of this medicine.

Dronabinol may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

To stimulate appetite in people with AIDS, dronabinol is usually taken 1 hour before lunch and 1 hour before dinner.

To prevent nausea and vomiting caused by chemotherapy:

• Take your first dose on an empty stomach, at least 30 minutes before eating.
• After your first dose, you may take dronabinol with or without food but take it at the same time in relation to your mealtimes for each treatment for chemotherapy.
• Dronabinol is usually given 1 to 3 hours before your chemotherapy treatment, and then every 2 to 4 hours (up to 6 doses per day).

• What happens if I miss a dose?

  Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

  Common side effects of dronabinol may include:

  • feeling “high”;
  • dizziness, drowsiness, thinking problems;
  • unusual thoughts or fears;
  • feelings of extreme happiness; or
  • nausea, vomiting, stomach pain.